Interaction

curated

Interaction Scheme

Molecule

Norfloxacin
Norfloxacin

c = 10.0 µM

Host

Scx4
sCx4

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 1.70⋅104 M-1
Kd =
logKa = 4.23
T 25.0 °C ≈ 298 K
Energy kJ mol-1 kcal mol-1
ΔG = -24.15 -5.77
These are the specifications of the determination of the experimental results.
Detection Method: Direct
Assay Type: Direct Binding Assay
Technique: Fluorescence
𝛌ex = 305.0 nm
Detailed information about the solvation.
Solvent System Buffer System 500 mM phosphate pH-6.0
Solvents water
Additives Disodium hydrog...
Sodium dihydrog...
Source of Concentration
Total concentration 500.0 mM
pH 6.0
Please find here information about the dataset this interaction is part of.
Citation:

J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, SupraBank 2024, Study on the inclusion interaction of p-sulfonatocalix[n]arenes with norfloxacin (dataset). https://doi.org/10.34804/supra.2021092884

Link: https://doi.org/10.34804/supra.2021092884
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Please find here information about the scholarly article describing the results derived from that data.
Citation:

J. Chao, K. Song, H. Wang, Z. Guo, B. Zhang, T. Zhang, Physics and Chemistry of Liquids 2016, 55, 579–588.

Link: https://doi.org/10.1080/00319104.2016.1250270
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Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Norfloxacin (0.001176470588235294 M) and sCx4 (0 — 0.002352941176470588 M).