𝜈 | Molecule 1 : 1 Host | ||
Ka = | 20.0 | ± 1.0 | M-1 |
Kd = | |||
logKa = | |||
T | 20.0 °C | ||
Energy | kJ mol-1 | kcal mol-1 | |||
---|---|---|---|---|---|
ΔG | = | -7.3 | ± 0.12 | -1.74 | ± 0.03 |
Detection Method: | Direct | ||
Assay Type: | Direct Binding Assay | ||
Technique: | Nuclear Magnetic Resonance |
Solvent System | Buffer System | 250 mM deuterated phosphate pD-7.0 |
Solvents | Deuterium Oxide | |
Additives | Disodium hydrog... | 144.5 mM |
Sodium dihydrog... | 105.5 mM | |
Source of Concentration | real | |
Total concentration | 250.0 mM | |
pH | 7.0 |
Citation: |
J. Ede, P. Cragg, M. Sambrook, SupraBank 2024, Comparison of Binding Affinities of Water-Soluble Calixarenes with the Organophosphorus Nerve Agent Soman (GD) and Commonly-Used Nerve Agent Simulants (dataset). https://doi.org/10.34804/supra.20210928394 |
Link: | https://doi.org/10.34804/supra.20210928394 |
Export: | BibTex | RIS | EndNote |
Citation: |
J. Ede, P. Cragg, M. Sambrook, Molecules 2018, 23, 207. |
Link: | https://doi.org/10.3390/molecules23010207 |
Export: | BibTex | RIS | EndNote |
The plot depicts the binding isotherm simulation of a 1:1 interaction of Pinacolyl methylphosphonic acid (1.0 M) and sCx4 (0 — 2.0 M).