Interaction Scheme
Molecule
Berberine chloride
c = 19.3 µM
Host
sCx8
c = 0.0 — 315.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 3.02⋅105 | ± 4.19⋅104 | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -31.28 | ± 0.35 | -7.48 | ± 0.08 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | ||
| Assay Type: | Direct Binding Assay | ||
| Technique: | Absorbance | ||
Detailed information about the solvation.
| Solvent System | Buffer System | phosphate pH-6.96 |
| Solvents | water | |
| Additives | Disodium hydrog... | 3.7 mM |
| Potassium dihyd... | 3.7 mM | |
| Source of Concentration | real | |
| Total concentration | 7.4 mM | |
| pH | 6.96 |
Please find here information about the dataset this interaction is part of.
| Citation: |
L. Biczók, M. Megyesi, SupraBank 2025, Considerable fluorescence enhancement upon supramolecular complex formation between berberine and p-sulfonated calixarenes (dataset). https://doi.org/10.34804/supra.2021092865 |
| Link: | https://doi.org/10.34804/supra.2021092865 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
M. Megyesi, L. Biczók, Chemical Physics Letters 2006, 424, 71–76. |
| Link: | https://doi.org/10.1016/j.cplett.2006.04.016 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Berberine chloride (6.622516556291391e-05 M) and sCx8 (0 — 0.00013245033112582781 M).
Please sign in: customize the simulation by signing in to the SupraBank.
