Interaction Scheme
Molecule
Berberine chloride
c = 20.0 µM
Host
β-CD
c = 0.0 — 3000.0 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 87.0 | ± | M-1 |
| Kd = | |||
| logKa = | |||
| T | 25.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -11.07 | ± 0.0 | -2.65 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Direct | |||
| Assay Type: | Direct Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 348.0 nm | ||
| 𝛌em | = | 530.0 nm | ||
| Ibound⁄Ifree | = | 10.0 | ||
Detailed information about the solvation.
| Solvent System | Buffer System | phosphate pH-7.2 |
| Solvents | water | |
| Source of Concentration | ||
| pH | 7.2 |
Please find here information about the dataset this interaction is part of.
| Citation: |
J. Yu, F. Wei, W. Gao, C. Zhao, SupraBank 2024, Thermodynamic study on the effects of β-cyclodextrin inclusion with berberine (dataset). https://doi.org/10.34804/supra.20210928305 |
| Link: | https://doi.org/10.34804/supra.20210928305 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
J.-S. Yu, F.-D. Wei, W. Gao, C.-C. Zhao, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2002, 58, 249–256. |
| Link: | https://doi.org/10.1016/S1386-1425(01)00536-4 |
| Export: | BibTex | RIS | EndNote |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Berberine chloride (0.22988505747126436 M) and β-CD (0 — 0.45977011494252873 M).
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