Interaction

curated

Interaction Scheme

Molecule

Untitled
Dopamine hydrochloride

Host

Cb7
CB7

c = 2.55 µM

Indicator

Dapi 2h
DAPI 2H+

c = 4.59 µM

Binding Properties

𝜈 Molecule 1 : 1 Host
Ka = 1.00⋅105 ± M-1
Kd =
logKa = 5.0 ± 0.0
T 23.0 °C ≈ 296 K
Energy kJ mol-1 kcal mol-1
ΔG = -28.35 ± 0.0 -6.78 ± 0.0
These are the specifications of the determination of the experimental results.
Detection Method: Competitive
Assay Type: Competitive Binding Assay
Technique: Fluorescence
𝛌ex = 361.0 nm
𝛌em = 476.0 nm
Ibound⁄Ifree = 8.0
Detailed information about the solvation.
Solvent System Single Solvent
Solvent water
Please find here information about the dataset this interaction is part of.
Citation:

Z. Miskolczy, L. Biczók, M. Megyesi, I. Jablonkai, SupraBank 2024, Inclusion Complex Formation of Ionic Liquids and Other Cationic Organic Compounds with Cucurbit[7]uril Studied by 4′,6-Diamidino-2-phenylindole Fluorescent Probe (dataset). https://doi.org/10.34804/supra.20210928317

Link: https://doi.org/10.34804/supra.20210928317
Export: BibTex | RIS | EndNote
Please find here information about the scholarly article describing the results derived from that data.
Citation:

Z. Miskolczy, L. Biczók, M. Megyesi, I. Jablonkai, J. Phys. Chem. B 2009, 113, 1645–1651.

Link: https://doi.org/10.1021/jp8098329
Export: BibTex | RIS | EndNote |

Binding Isotherm Simulations

The plot depicts the binding isotherm simulation of a 1:1 interaction of Dopamine hydrochloride (0.0002 M) and CB7 (0 — 0.0004 M).