Interactions of 100 mM sodium phosphate buffer pH-7.2
Info |
|
Molecule |
|
Molecule |
|
Partner |
|
Partner |
|
Ka |
log Ka |
Conditions |
Supplement |
|
|
Dibucaine hy...
|
|
Dibucaine hy...
|
|
sCx5 sodium ...
|
|
sCx5 sodium ...
|
|
2600.0 M-1
|
3.41
|
buffer
|
|
|
|
2,6-Dimethyl...
|
|
2,6-Dimethyl...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
6760.83 M-1
|
3.83
|
buffer
|
|
|
|
Lidocaine
|
|
Lidocaine
|
|
sCx5 sodium ...
|
|
sCx5 sodium ...
|
|
1120.0 M-1
|
3.05
|
buffer
|
|
|
|
Diquat
|
|
Diquat
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
7.95⋅105 M-1
|
5.9
|
buffer
|
|
|
|
2,6-TNS
|
|
2,6-TNS
|
|
Mono[2-O-(2-...
|
|
Mono[2-O-(2-...
|
|
3030.0 M-1
|
3.48
|
buffer
|
|
|
|
Quinidine
|
|
Quinidine
|
|
sCx4
|
|
sCx4
|
|
3800.0 M-1
|
3.58
|
buffer
|
|
|
|
Cinchonidine
|
|
Cinchonidine
|
|
stCx4
|
|
stCx4
|
|
7400.0 M-1
|
3.87
|
buffer
|
|
|
|
Quinidine
|
|
Quinidine
|
|
stCx4
|
|
stCx4
|
|
2400.0 M-1
|
3.38
|
buffer
|
|
|
|
Dehydrocoryd...
|
|
Dehydrocoryd...
|
|
β-CD
|
|
β-CD
|
|
588.0 M-1
|
2.77
|
buffer
|
|
|
|
Quinine
|
|
Quinine
|
|
sCx5
|
|
sCx5
|
|
4500.0 M-1
|
3.65
|
buffer
|
|
|
|
Rhodamine B
|
|
Rhodamine B
|
|
β-CD
|
|
β-CD
|
|
5100.0 M-1
|
3.71
|
buffer
|
|
|
|
2,6-TNS
|
|
2,6-TNS
|
|
Mono(6-O-a-m...
|
|
Mono(6-O-a-m...
|
|
2410.0 M-1
|
3.38
|
buffer
|
|
|
|
Quinidine
|
|
Quinidine
|
|
sCx5
|
|
sCx5
|
|
3600.0 M-1
|
3.56
|
buffer
|
|
|
|
4-methylpyri...
|
|
4-methylpyri...
|
|
sCx5
|
|
sCx5
|
|
267.0 M-1
|
2.43
|
buffer
|
|
|
|
Acridine red
|
|
Acridine red
|
|
Mono[2-O-(2-...
|
|
Mono[2-O-(2-...
|
|
2400.0 M-1
|
3.38
|
buffer
|
|
|
|
1,8-ANS
|
|
1,8-ANS
|
|
Mono(6-O-a-m...
|
|
Mono(6-O-a-m...
|
|
69.0 M-1
|
1.84
|
buffer
|
|
|
|
2,6-Dimethyl...
|
|
2,6-Dimethyl...
|
|
sCx5
|
|
sCx5
|
|
2900.0 M-1
|
3.46
|
buffer
|
|
|
|
Lidocaine
|
|
Lidocaine
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
770.0 M-1
|
2.89
|
buffer
|
|
|
|
4,4'-Dipyridine
|
|
4,4'-Dipyridine
|
|
stCx4
|
|
stCx4
|
|
49.0 M-1
|
1.69
|
buffer
|
|
|
|
procainamide...
|
|
procainamide...
|
|
sCx5 sodium ...
|
|
sCx5 sodium ...
|
|
1780.0 M-1
|
3.25
|
buffer
|
|
|
|
1,8-ANS
|
|
1,8-ANS
|
|
Mono[2-O-(2-...
|
|
Mono[2-O-(2-...
|
|
260.0 M-1
|
2.41
|
buffer
|
|
|
|
Acridine red
|
|
Acridine red
|
|
Mono(6-O-a-m...
|
|
Mono(6-O-a-m...
|
|
1790.0 M-1
|
3.25
|
buffer
|
|
|
|
Tetracaine h...
|
|
Tetracaine h...
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
519.0 M-1
|
2.72
|
buffer
|
|
|
|
Cinchonidine
|
|
Cinchonidine
|
|
sCx5
|
|
sCx5
|
|
3100.0 M-1
|
3.49
|
buffer
|
|
|
|
Procaine hyd...
|
|
Procaine hyd...
|
|
sCx5 sodium ...
|
|
sCx5 sodium ...
|
|
1630.0 M-1
|
3.21
|
buffer
|
|
|
|
Procaine hyd...
|
|
Procaine hyd...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
5090.0 M-1
|
3.71
|
buffer
|
|
|
|
Rhodamine B
|
|
Rhodamine B
|
|
Mono[2-O-(2-...
|
|
Mono[2-O-(2-...
|
|
3840.0 M-1
|
3.58
|
buffer
|
|
|
|
Lidocaine hy...
|
|
Lidocaine hy...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
6560.0 M-1
|
3.82
|
buffer
|
|
|
|
Cinchonine
|
|
Cinchonine
|
|
stCx4
|
|
stCx4
|
|
4300.0 M-1
|
3.63
|
buffer
|
|
|
|
Tetracaine h...
|
|
Tetracaine h...
|
|
sCx5 sodium ...
|
|
sCx5 sodium ...
|
|
547.0 M-1
|
2.74
|
buffer
|
|
|
|
2,6-TNS
|
|
2,6-TNS
|
|
β-CD
|
|
β-CD
|
|
3700.0 M-1
|
3.57
|
buffer
|
|
|
|
Procaine hyd...
|
|
Procaine hyd...
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
623.0 M-1
|
2.79
|
buffer
|
|
|
|
Cinchonidine
|
|
Cinchonidine
|
|
sCx4
|
|
sCx4
|
|
4100.0 M-1
|
3.61
|
buffer
|
|
|
|
MVI2
|
|
MVI2
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
8680.0 M-1
|
3.94
|
buffer
|
|
|
|
1,8-ANS
|
|
1,8-ANS
|
|
β-CD
|
|
β-CD
|
|
102.0 M-1
|
2.01
|
buffer
|
|
|
|
procainamide...
|
|
procainamide...
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
649.0 M-1
|
2.81
|
buffer
|
|
|
|
Diquat
|
|
Diquat
|
|
sCx5
|
|
sCx5
|
|
3.23⋅106 M-1
|
6.51
|
buffer
|
|
|
|
2-methylpyri...
|
|
2-methylpyri...
|
|
sCx5
|
|
sCx5
|
|
432.0 M-1
|
2.64
|
buffer
|
|
|
|
Tetracaine h...
|
|
Tetracaine h...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
2690.0 M-1
|
3.43
|
buffer
|
|
|
|
Cinchonine
|
|
Cinchonine
|
|
sCx5
|
|
sCx5
|
|
2600.0 M-1
|
3.41
|
buffer
|
|
|
|
Palmatine
|
|
Palmatine
|
|
β-CD
|
|
β-CD
|
|
629.0 M-1
|
2.8
|
buffer
|
|
|
|
Dibucaine hy...
|
|
Dibucaine hy...
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
1550.0 M-1
|
3.19
|
buffer
|
|
|
|
Quinine
|
|
Quinine
|
|
stCx4
|
|
stCx4
|
|
6600.0 M-1
|
3.82
|
buffer
|
|
|
|
MVI2
|
|
MVI2
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
9.33⋅104 M-1
|
4.97
|
buffer
|
|
|
|
Acridine red
|
|
Acridine red
|
|
β-CD
|
|
β-CD
|
|
2630.0 M-1
|
3.42
|
buffer
|
|
|
|
Pyridine
|
|
Pyridine
|
|
stCx4
|
|
stCx4
|
|
55.0 M-1
|
1.74
|
buffer
|
|
|
|
2,2'-Bipyridine
|
|
2,2'-Bipyridine
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
84.0 M-1
|
1.92
|
buffer
|
|
|
|
4,4'-Dipyridine
|
|
4,4'-Dipyridine
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
44.0 M-1
|
1.64
|
buffer
|
|
|
|
Rhodamine B
|
|
Rhodamine B
|
|
Mono(6-O-a-m...
|
|
Mono(6-O-a-m...
|
|
3300.0 M-1
|
3.52
|
buffer
|
|
|
|
2,6-Dimethyl...
|
|
2,6-Dimethyl...
|
|
stCx4
|
|
stCx4
|
|
1520.0 M-1
|
3.18
|
buffer
|
|
|
|
1,10-Phenant...
|
|
1,10-Phenant...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
278.0 M-1
|
2.44
|
buffer
|
|
|
|
Cinchonine
|
|
Cinchonine
|
|
sCx4
|
|
sCx4
|
|
2000.0 M-1
|
3.3
|
buffer
|
|
|
|
Dibucaine hy...
|
|
Dibucaine hy...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
1.79⋅104 M-1
|
4.25
|
buffer
|
|
|
|
2-methylpyri...
|
|
2-methylpyri...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
1340.0 M-1
|
3.13
|
buffer
|
|
|
|
2,2'-Bipyridine
|
|
2,2'-Bipyridine
|
|
stCx4
|
|
stCx4
|
|
57.0 M-1
|
1.76
|
buffer
|
|
|
|
2-methylpyri...
|
|
2-methylpyri...
|
|
stCx4
|
|
stCx4
|
|
209.0 M-1
|
2.32
|
buffer
|
|
|
|
Diquat
|
|
Diquat
|
|
stCx4 sodium...
|
|
stCx4 sodium...
|
|
4.57⋅104 M-1
|
4.66
|
buffer
|
|
|
|
Pyridine
|
|
Pyridine
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
305.0 M-1
|
2.48
|
buffer
|
|
|
|
4-methylpyri...
|
|
4-methylpyri...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
520.0 M-1
|
2.72
|
buffer
|
|
|
|
Quinine
|
|
Quinine
|
|
sCx4
|
|
sCx4
|
|
2000.0 M-1
|
3.3
|
buffer
|
|
|
|
4-methylpyri...
|
|
4-methylpyri...
|
|
stCx4
|
|
stCx4
|
|
139.0 M-1
|
2.14
|
buffer
|
|
|
|
Pyridine
|
|
Pyridine
|
|
sCx5
|
|
sCx5
|
|
73.0 M-1
|
1.86
|
buffer
|
|
|
|
procainamide...
|
|
procainamide...
|
|
sCx4 sodium ...
|
|
sCx4 sodium ...
|
|
1.02⋅104 M-1
|
4.01
|
buffer
|
|
|
|
1,10-Phenant...
|
|
1,10-Phenant...
|
|
stCx4
|
|
stCx4
|
|
285.0 M-1
|
2.45
|
buffer
|
|
|
|
Methyl viologen
|
|
Methyl viologen
|
|
sCx5
|
|
sCx5
|
|
2.51⋅105 M-1
|
5.4
|
buffer
|
|