Interaction Scheme
Molecule
Berberine chloride
Host
CB7
c = 2.55 µM
Indicator
DAPI 2H+
c = 4.59 µM
Binding Properties
| 𝜈 | Molecule 1 : 1 Host | ||
| Ka = | 1.60⋅106 | ± | M-1 |
| Kd = | |||
| logKa = | |||
| T | 23.0 °C | ||
| Energy | kJ mol-1 | kcal mol-1 | |||
|---|---|---|---|---|---|
| ΔG | = | -35.18 | ± 0.0 | -8.41 | ± 0.0 |
These are the specifications of the determination of the experimental results.
| Detection Method: | Competitive | |||
| Assay Type: | Competitive Binding Assay | |||
| Technique: | Fluorescence | |||
| 𝛌ex | = | 361.0 nm | ||
| 𝛌em | = | 476.0 nm | ||
| Ibound⁄Ifree | = | 8.0 | ||
Detailed information about the solvation.
| Solvent System | Single Solvent |
| Solvent | water |
Please find here information about the dataset this interaction is part of.
| Citation: |
Z. Miskolczy, L. Biczók, M. Megyesi, I. Jablonkai, SupraBank 2024, Inclusion Complex Formation of Ionic Liquids and Other Cationic Organic Compounds with Cucurbit[7]uril Studied by 4′,6-Diamidino-2-phenylindole Fluorescent Probe (dataset). https://doi.org/10.34804/supra.20210928317 |
| Link: | https://doi.org/10.34804/supra.20210928317 |
| Export: | BibTex | RIS | EndNote |
Please find here information about the scholarly article describing the results derived from that data.
| Citation: |
Z. Miskolczy, L. Biczók, M. Megyesi, I. Jablonkai, J. Phys. Chem. B 2009, 113, 1645–1651. |
| Link: | https://doi.org/10.1021/jp8098329 |
| Export: | BibTex | RIS | EndNote | |
Binding Isotherm Simulations
The plot depicts the binding isotherm simulation of a 1:1 interaction of Berberine chloride (1.25e-05 M) and CB7 (0 — 2.5e-05 M).
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