Interactions of 10 mM HEPES buffer pH-7.4
Info |
|
Molecule |
|
Molecule |
|
Partner |
|
Partner |
|
Ka |
log Ka |
Conditions |
Supplement |
|
|
Ac-GGK-OH
|
|
Ac-GGK-OH
|
|
sCx5-6C
|
|
sCx5-6C
|
|
179.0 M-1
|
2.25
|
buffer
|
|
|
|
L-Lys
|
|
L-Lys
|
|
sCx5
|
|
sCx5
|
|
701.0 M-1
|
2.85
|
buffer
|
|
|
|
tiludronate
|
|
tiludronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
8.31⋅106 M-1
|
6.92
|
buffer
|
Fluorescein
|
|
|
Lucigenin
|
|
Lucigenin
|
|
sCx4-12C
|
|
sCx4-12C
|
|
5.70⋅106 M-1
|
6.76
|
buffer
|
|
|
|
Lucigenin
|
|
Lucigenin
|
|
sCx6-12C
|
|
sCx6-12C
|
|
1.00⋅107 M-1
|
7.0
|
buffer
|
|
|
|
L-Arg
|
|
L-Arg
|
|
sCx5-6C
|
|
sCx5-6C
|
|
6320.0 M-1
|
3.8
|
buffer
|
|
|
|
Ac-GKG-NH2
|
|
Ac-GKG-NH2
|
|
sCx5-6C
|
|
sCx5-6C
|
|
8980.0 M-1
|
3.95
|
buffer
|
|
|
|
P-TPE
|
|
P-TPE
|
|
gCx5-6C
|
|
gCx5-6C
|
|
8.40⋅107 M-1
|
7.92
|
buffer
|
|
|
|
zoledronate
|
|
zoledronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.34⋅107 M-1
|
7.13
|
buffer
|
Fluorescein
|
|
|
clodronate
|
|
clodronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
6.60⋅107 M-1
|
7.82
|
buffer
|
Fluorescein
|
|
|
L-Lys
|
|
L-Lys
|
|
sCx4
|
|
sCx4
|
|
1110.0 M-1
|
3.05
|
buffer
|
|
|
|
lysophosphat...
|
|
lysophosphat...
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.60⋅108 M-1
|
8.2
|
buffer
|
Fluorescein
|
|
|
RB
|
|
RB
|
|
gCx5-6C
|
|
gCx5-6C
|
|
9.60⋅107 M-1
|
7.98
|
buffer
|
Fluorescein
|
|
|
ibandronate
|
|
ibandronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
3.01⋅105 M-1
|
5.48
|
buffer
|
Fluorescein
|
|
|
1,8-ANS
|
|
1,8-ANS
|
|
gCx5-6C
|
|
gCx5-6C
|
|
3.00⋅106 M-1
|
6.48
|
buffer
|
|
|
|
2,6-TNS
|
|
2,6-TNS
|
|
gCx5-6C
|
|
gCx5-6C
|
|
4.40⋅106 M-1
|
6.64
|
buffer
|
|
|
|
Oxaliplatin
|
|
Oxaliplatin
|
|
Guanidinocal...
|
|
Guanidinocal...
|
|
2.60⋅105 M-1
|
5.41
|
buffer
|
Fluorescein
|
|
|
chlorambucil
|
|
chlorambucil
|
|
Guanidinocal...
|
|
Guanidinocal...
|
|
1.80⋅105 M-1
|
5.26
|
buffer
|
Fluorescein
|
|
|
TPS
|
|
TPS
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.40⋅106 M-1
|
6.15
|
buffer
|
|
|
|
alendronate
|
|
alendronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.80⋅105 M-1
|
5.26
|
buffer
|
Fluorescein
|
|
|
etidronate
|
|
etidronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.24⋅107 M-1
|
7.09
|
buffer
|
Fluorescein
|
|
|
Lucigenin
|
|
Lucigenin
|
|
sCx5
|
|
sCx5
|
|
1.48⋅106 M-1
|
6.17
|
buffer
|
|
|
|
6-((2-((2-am...
|
|
6-((2-((2-am...
|
|
sCx5-6C
|
|
sCx5-6C
|
|
5.41⋅104 M-1
|
4.73
|
buffer
|
|
|
|
oleate
|
|
oleate
|
|
Guanidinocal...
|
|
Guanidinocal...
|
|
6.10⋅106 M-1
|
6.79
|
buffer
|
Fluorescein
|
|
|
L-Arg
|
|
L-Arg
|
|
sCx4-5C
|
|
sCx4-5C
|
|
16.0 M-1
|
1.2
|
buffer
|
|
|
|
L-Arg
|
|
L-Arg
|
|
sCx5
|
|
sCx5
|
|
1020.0 M-1
|
3.01
|
buffer
|
|
|
|
Trimethylami...
|
|
Trimethylami...
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.61⋅104 M-1
|
4.21
|
buffer
|
Uranine
|
|
|
L-Arg
|
|
L-Arg
|
|
sCx4
|
|
sCx4
|
|
1860.0 M-1
|
3.27
|
buffer
|
|
|
|
Lucigenin
|
|
Lucigenin
|
|
sCx4
|
|
sCx4
|
|
1.26⋅107 M-1
|
7.1
|
buffer
|
|
|
|
neridronate
|
|
neridronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.26⋅105 M-1
|
5.1
|
buffer
|
Fluorescein
|
|
|
AlPcS4
|
|
AlPcS4
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.70⋅108 M-1
|
8.23
|
buffer
|
Fluorescein
|
|
|
EY
|
|
EY
|
|
gCx4-OEG
|
|
gCx4-OEG
|
|
2.37⋅105 M-1
|
5.37
|
buffer
|
|
|
|
5, 10, 15, 2...
|
|
5, 10, 15, 2...
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.10⋅108 M-1
|
8.04
|
buffer
|
Fluorescein
|
|
|
Trimethylami...
|
|
Trimethylami...
|
|
sCx4
|
|
sCx4
|
|
65.5 M-1
|
1.82
|
buffer
|
Lucigenin
|
|
|
risedronate
|
|
risedronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
8.24⋅106 M-1
|
6.92
|
buffer
|
Fluorescein
|
|
|
Fluorescein
|
|
Fluorescein
|
|
gCx5-6C
|
|
gCx5-6C
|
|
5.00⋅106 M-1
|
6.7
|
buffer
|
|
|
|
Lucigenin
|
|
Lucigenin
|
|
sCx5-12C
|
|
sCx5-12C
|
|
2.70⋅107 M-1
|
7.43
|
buffer
|
|
|
|
spermine
|
|
spermine
|
|
sCx4-12C
|
|
sCx4-12C
|
|
8.40⋅106 M-1
|
6.92
|
buffer
|
Lucigenin
|
|
|
spermine
|
|
spermine
|
|
sCx6-12C
|
|
sCx6-12C
|
|
3.70⋅107 M-1
|
7.57
|
buffer
|
Lucigenin
|
|
|
spermine
|
|
spermine
|
|
sCx5-12C
|
|
sCx5-12C
|
|
5.90⋅107 M-1
|
7.77
|
buffer
|
Lucigenin
|
|
|
PFOS
|
|
PFOS
|
|
gCx5-6C
|
|
gCx5-6C
|
|
3.50⋅107 M-1
|
7.54
|
buffer
|
Uranine
|
|
|
Adenosine tr...
|
|
Adenosine tr...
|
|
gCx5-6C
|
|
gCx5-6C
|
|
4.70⋅108 M-1
|
8.67
|
buffer
|
Fluorescein
|
|
|
L-Lys
|
|
L-Lys
|
|
sCx4-5C
|
|
sCx4-5C
|
|
148.0 M-1
|
2.17
|
buffer
|
|
|
|
methotrexate
|
|
methotrexate
|
|
Guanidinocal...
|
|
Guanidinocal...
|
|
7.30⋅105 M-1
|
5.86
|
buffer
|
Fluorescein
|
|
|
L-Lys
|
|
L-Lys
|
|
sCx5-6C
|
|
sCx5-6C
|
|
1.07⋅104 M-1
|
4.03
|
buffer
|
|
|
|
perfluorooct...
|
|
perfluorooct...
|
|
gCx5-6C
|
|
gCx5-6C
|
|
1.70⋅107 M-1
|
7.23
|
buffer
|
Uranine
|
|
|
pamidronate
|
|
pamidronate
|
|
gCx5-6C
|
|
gCx5-6C
|
|
5.37⋅106 M-1
|
6.73
|
buffer
|
Fluorescein
|
|
|
Fluorescein
|
|
Fluorescein
|
|
Guanidinocal...
|
|
Guanidinocal...
|
|
1.90⋅107 M-1
|
7.28
|
buffer
|
|